Nanotechnology : Cambridge

3Dm, Inc.

Benj — Mon, 21 Aug 2006 20:11:02 +0000

Ticker Id

Web url

http://www.puramatrix.com/

Contact Email

contact@puramatrix.com

Short description

Street address

PO Box 425025

Zip or postal code

02142

Telephone

1-877-430-9595

Fax

Foundation date

Ceo, president

Zen Chu

Number of employees

Long description

PuraMatrix is 3DM's patented product line of synthetic self-assembling peptide hydrogels invented at MIT. PuraMatrix is the leading commcial synthetic scaffold for 3D cell culture, cancer biology, drug discovery, tissue engineering, bioproduction, and cell therapy research. PuraMatrix is composed of a simple 16 amino acid peptide monomer 1% weight/volume in tissue culture water, which self-assembles in the presence of salt to form ECM-scale nanofibers, that in turn self-assemble into extremely stable, injectable, biocompatible and biodegradable hydrogels. The gels work by coating surfaces or encapsulating cells, allowing for the proper three dimensional (3-D) culture across most cell types, including cell-based assays for neurite outgrowth, angiogenesis, cell migration, cancer invasion, and hepatocyte toxicity. This reproducible integrin-free scaffold can be customized according to the desired microenvironment to closely model the in vivo milieu along with growth factors, cytokines, integrin sequences, and other bioactive molecules.

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Patents

Advanced Magnetics, Inc.

Benj — Wed, 16 Aug 2006 14:08:59 +0000

Ticker Id

Web url

http://www.advancedmagnetics.com/

Contact Email

Short description

Street address

61 Mooney St.

Zip or postal code

02138

Telephone

(617) 497-2070

Fax

(617) 547-2445

Foundation date

Ceo, president

Number of employees

Long description

Combidex is our investigational molecular imaging agent consisting of iron oxide nanoparticles for use in conjunction with magnetic resonance imaging (MRI) to aid in the differentiation of cancerous from non-cancerous lymph nodes. Combidex received an approvable letter, subject to certain conditions, from the U.S. Food and Drug Administration (FDA) in June 2000. In September 2004, we submitted a complete response to the approvable letter, which was accepted by the FDA and assigned a user fee goal date of March 30, 2005.

Ferumoxytol, the next-generation product in our development pipeline, is currently in Phase III multi-center clinical trials for use as an iron replacement therapeutic in anemic chronic kidney disease patients, whether or not on dialysis. Exploratory Phase II clinical trials of ferumoxytol for use as a contrast agent in magnetic resonance angiography (MRA) are currently ongoing.

Feridex I.V.О®, our liver contrast agent, is approved and marketed in Europe, Japan, the United States and other countries. GastroMARK, our oral contrast agent used for delineating the bowel in MRI, is approved and marketed in Europe, the United States and other countries.

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Patents

AMAG Pharmaceuticals, Inc.

Benj — Tue, 07 Aug 2007 13:37:16 +0000

Ticker Id

Web url

http://www.amagpharma.com/

Contact Email

contactus@amagpharma.com

Short description

Street address

125 CambridgePark Drive 6th Floor

Zip or postal code

02140

Telephone

(617) 498–3300

Fax

(617) 499-3361

Foundation date

Ceo, president

Number of employees

Long description

Our core technology is based on the characteristic properties of extremely small, coated superparamagnetic iron oxide nanoparticles. Our core competencies include the ability to design such nanoparticles for particular applications, to manufacture the nanoparticles in controlled sizes and to cover the nanoparticles with different coatings depending upon the application for which they will be used. Our technology and expertise enable us to synthesize, sterilize and stabilize these iron oxide nanoparticles in a manner necessary for use in pharmaceutical products such as iron replacement therapeutics and magnetic resonance imaging (MRI) contrast agents.

Our iron oxide nanoparticles are composed of bioavailable iron that is easily absorbed by the body and incorporated into the body's iron stores. As a result, products using our core technology are well suited for use in intravenous (IV) iron replacement therapy. Additionally, the superparamagnetic characteristic of our products results in nanoparticles that become strongly magnetic when placed in a magnetic field, but lose their magnetism once the field is removed. Therefore, use of our nanoparticles results in magnetic resonance images that increase the information available to the reviewing physicians.

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Patents

Cambridge University : Nanoscience Centre

Benj — Wed, 16 Aug 2006 21:19:21 +0000

Ticker Id

Web url

http://www.nanoscience.cam.ac.uk/centre/index.html

Contact Email

enquiries@nanoscience.cam.ac.uk

Short description

Street address

University of Cambridge Nanoscience Centre, 11 J J Thomson Ave

Zip or postal code

CB3 0FF

Telephone

+44 (0)1223 760304

Fax

+44 (0)1223 760306

Foundation date

Ceo, president

Number of employees

Long description

The Nanoscience Centre is a new building occupying a site at the north east corner of the Cavendish Laboratories. The main activity in the building is making individual devices or structures which are only a few nanometres in size and then measuring how they work. The building was completed in early 2003.

The building is of one storey throughout. Offices for researchers and technical support, together with a small meeting room have been designed to be set into the berm so as to reduce their visibility from Clerk Maxwell Road. To the west of the office area is a laboratory which is split into a clean room facility for the fabrication of the nanometre scale devices and structures, and laboratory space for characterisation of the same. The size of these devices is already much smaller than the dust particles filling the air around us.

Air in the clean room is forced through fine filters in the ceiling of the building and recirculated along with a percentage of fresh air. The filtered air in the clean room prevents contamination of the devices by the atmospheric dust. Within this room various types of patterning and fabrication will be carried out.

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Patents

Cambridge NanoTech Inc.

DJ MacLeod — Wed, 16 Aug 2006 17:37:51 +0000

Ticker Id

Web url

http://www.cambridgenanotech.com/

Contact Email

info@cambridgenanotech.com

Short description

Street address

143 Binney Street

Zip or postal code

02142

Telephone

+1-617-251-6639

Fax

+1-509-479-0343

Foundation date

Ceo, president

Jill S. Becker, Ph.D. & Douwe J. Monsma, Ph.D

Number of employees

Long description

Cambridge NanoTech is the ALD systems and services market leader having sold more than 70 ALD systems worldwide. At the cutting edge of nano-materials development, Cambridge NanoTech is focused on the design, manufacture and marketing affordable Atomic Layer Deposition (ALD) systems for researchers worldwide.

The Savannah Series system has been widely adopted in a variety of coating applications such as; semiconductor, optics, thin-film displays, and bio-compatible coatings.

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Patents

E Ink Corporation

Benj — Wed, 30 Aug 2006 13:45:21 +0000

Ticker Id

Web url

http://www.eink.com/

Contact Email

Short description

Street address

733 Concord Avenue

Zip or postal code

02138

Telephone

617-499-6000

Fax

617-499-6200

Foundation date

Ceo, president

Number of employees

Long description

Products made with E Ink's revolutionary electronic ink possess a paper-like high contrast appearance, ultra-low power consumption and a thin, light form. E Ink's technology is ideal for many consumer and industrial applications spanning handheld devices, watches, clocks and public information and promotional signs. Future technology developments will enable many new applications through ultra-thin, lightweight, rugged, flexible, full color displays.

E Ink has commercialized many different forms of "Electronic Paper" solutions over the past seven years. In April 2004, E Ink launched an active-matrix display product with SONY in Japan based on our unique electronic display material which SONY values for its brightness, high contrast, and low power - just like paper. Recent press announcements with Seiko (watches), Casio (clocks), Vossloh (transportation signage) and NeoLux (retail signage) illustrate the increasing demand for commercialization of E Ink's electronic ink technology.

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Patents

Evolved Nanomaterial Sciences, Inc. (ENS, Ensbio)

Benj — Sat, 19 Aug 2006 18:02:56 +0000

Ticker Id

Web url

http://www.ensbio.com/

Contact Email

Short description

Street address

675 Massachusetts Avenue, 14th Floor

Zip or postal code

02139

Telephone

617-441-5100

Fax

617-902-2700

Foundation date

Ceo, president

Robert Pucciariello

Number of employees

Long description

Novel approaches integrating smart nanomaterial design with process technology to solve pressing problems in separations. Our first product family under development provides reliable, scaleable chiral resolution solutions for pharmaceutical and specialty chmical applications.

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Patents

Flagship Ventures

Benj — Fri, 25 Aug 2006 16:54:51 +0000

Ticker Id

Web url

http://www.flagshipventures.com/

Contact Email

Short description

Street address

One Memorial Drive, 7th Floor

Zip or postal code

02142

Telephone

617.868.1888

Fax

617.868.1115

Foundation date

Ceo, president

Number of employees

Long description

Headquartered in Cambridge, MA, Flagship Ventures was founded in 1999 and manages $700 million in capital. Prior to its founding, Flagship's principals were involved as founders or investors in over 100 firms including: Adolor, AltaVista, Anesta, Antigenics, Aspect Medical, Astral Point, Celera Genomics, ChemGenics Pharmaceuticals, Color Kinetics, Chantry Networks, Cytyc, DataSage, Exact Sciences, IDEXX, PerSeptive Biosystems, Somatogen, Telecorp PCS and TripAdvisor.

The Flagship investment team consists of 10 professionals and is led by co-founders Noubar Afeyan and Ed Kania. Complementing our internal team is our extensive network of academic and industrial advisors who are actively engaged in evaluating and helping develop our new ventures. Extending over a period of 20 years, our entrepreneurship and investment experience comes from founding over 30 successful new ventures while funding and building over 100 more.

To maximize the returns to our investors, we combine our experience, our passion for innovation, our focus on value creation and our commitment to the success of each company's leadership team.

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Patents

GVD Corp.

vinay1210 — Tue, 25 Dec 2007 08:42:33 +0000

Ticker Id

Web url

http://www.gvdcorp.com

Contact Email

info@gvdcorp.com

Short description

Street address

19 Blackstone Street, Suite 1

Zip or postal code

02139

Telephone

(617) 661-0060

Fax

Foundation date

Ceo, president

Number of employees

Long description

GVD Corporation is a surface technology company that has pioneered an exciting breakthrough in nanotechnology, producing engineered polymer coatings that are unattainable using conventional technologies. GVD’s technology is uniquely suited to meet the growing demands for super-thin coatings for medical devices, membranes, textiles, and consumer goods as well as a wide range of other applications, both every day and cutting edge. GVD’s technology can create dramatically improved products as well as brand new products for its customers.

No other technology on the market can lay claim to the breadth of properties and coating flexibility attainable through GVD’s process. Although there are coatings on the market that can achieve some of the properties of GVD’s coatings, none possess the range of properties, technical integrity, thinness and uniformity at a cost as affordable as GVD’s process. Additionally, no commercial coating processes can produce nano-scale coatings on such a broad range of materials, geometries, and sizes, particularly micro- and nano-sized.

GVD works closely with its customers to customize and develop coatings for specific applications. GVD provides licenses to its technology, systems sales, and research & development services. In the future, GVD will provide coating services.

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Patents

Harvard University: Center for Nanoscale Systems ( CNS )

Benj — Sun, 27 Aug 2006 12:23:24 +0000

Ticker Id

Web url

http://www.cns.fas.harvard.edu/

Contact Email

info@cns.fas.harvard.edu

Short description

Street address

17 Oxford Street

Zip or postal code

02138

Telephone

617-384-7245

Fax

617-384-7302

Foundation date

Ceo, president

Number of employees

Long description

CNS is the Center for Nanoscale Systems, which is a part of the Faculty of Arts and Sciences (FAS) at Harvard University. Until April of 2005, the Center existed under a different name, the Center for Imaging and Mesoscale Structures (CIMS).

CNS was created by FAS in 1999 to assist and support the research community of Harvard University researchers and collaborators. The inclusion of CNS in the National Nanotechnology Infrastructure Network (NNIN) in 2004 has expanded that function to include any and all other members of the larger research community both local and national, academic and non-academic who conduct research in any aspect of the large and growing field of nanoscale science.

CNS accomplishes this mission by purchasing, operating and maintaining large, centralized scientific facilities for use by users. CNS also provides training, and assistance to users to ensure that the next generation of scientists has the knowledge to answer the questions being raised by the research of today. Development of new advanced facilities for the imaging and fabrication of nanoscale structures is also a high priority for CNS.

While operating user facilities is a large component of CNS’ operation, it is not the only contribution of the Center to the scientific community of Harvard and beyond. For example, CNS hosts seminars and provides seminar support to Harvard faculty members; has Seed Money and Visiting Scientist Programs to financially support faculty research efforts; provides cost-sharing support to facilitate the acquisition of new equipment facilities; hosts NSF Research Experience for Undergraduates (REU) students; and has CNS technical staff members who teach and guest lecture in Harvard classes.

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Patents

Harvard University: Division of Engineering and Applied Sciences, R. M. Westervelt group

Benj — Thu, 24 Aug 2006 16:42:54 +0000

Ticker Id

Web url

http://meso.deas.harvard.edu/default.html

Contact Email

Short description

Street address

Westervelt Lab, Gordon McKay Laboratory of Applied Science, 9 Oxford Street

Zip or postal code

02138

Telephone

Fax

Foundation date

Ceo, president

Number of employees

Long description

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Patents

Harvard University: George M. Whitesides Research Group

Benj — Thu, 24 Aug 2006 16:41:58 +0000

Ticker Id

Web url

http://gmwgroup.harvard.edu/

Contact Email

Short description

Street address

Harvard University, 12 Oxford Street

Zip or postal code

02138

Telephone

Fax

Foundation date

Ceo, president

Number of employees

Long description

Research Projects:

Biomimetics

Biosurface Chemistry

Complexity / Emergence

Material Science

MEMS

Microfluidics

Micro / Nanofabrication

Photonics

Polyvalency

Self-Assembly

Surface Science

Tools for Biophysics and Biology

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Patents

Harvard University: Leiber Group

Benj — Thu, 24 Aug 2006 16:45:12 +0000

Ticker Id

Web url

http://cmliris.harvard.edu/

Contact Email

Short description

Street address

Harvard University, 12 Oxford Street

Zip or postal code

02138

Telephone

Fax

Foundation date

Ceo, president

Number of employees

Long description

We use the bottom-up paradigm as the underlying approach for exploring application in diverse areas, including biology and medicine, photonics, and computing. Our laboratory has dedicated efforts in all of these areas.

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Patents

Harvard University: Materials Science Group

Benj — Thu, 24 Aug 2006 16:46:10 +0000

Ticker Id

Web url

http://www.deas.harvard.edu/matsci/index.html

Contact Email

Short description

Street address

Harvard University , 9 Oxford Street

Zip or postal code

02138

Telephone

(617) 495-4469

Fax

Foundation date

Ceo, president

Number of employees

Long description

Additional Commentaries and remarks

Patents

Harvard University: Nanoscale Science and Engineering Center (NSEC)

Benj — Thu, 24 Aug 2006 16:47:23 +0000

Ticker Id

Web url

http://www.nsec.harvard.edu/

Contact Email

Short description

Street address

Division of Engineering and Applied Sciences, Harvard University

Zip or postal code

02138

Telephone

Fax

Foundation date

Ceo, president

Number of employees

Long description

Through a close integration of research, education, and public outreach, the Center encourages and promotes the training of a diverse group of people to be leaders in this new interdisciplinary field. The NSEC is supported by the National Science Foundation.

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Patents

Harvard University: Park Research

Benj — Thu, 24 Aug 2006 16:44:06 +0000

Ticker Id

Web url

http://www.people.fas.harvard.edu/~hpark/

Contact Email

Short description

Street address

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street

Zip or postal code

02138

Telephone

Fax

Foundation date

Ceo, president

Number of employees

Long description

The general research interest of Hongkun Park is to develop detailed understanding of physics and chemistry of nanostructured materials and to apply this knowledge to possible technological applications. Current research efforts in his group focus on two specific aspects of this general goal: (1) To study electrical properties of individual molecules, clusters, carbon nanotubes, and their arrays using transport measurements and scanning probe microscopy and to test the viability of such structures for future molecular electronic applications, and (2) to develop synthetic schemes for transition-metal-oxide nanostructures with novel electronic and magnetic properties and to study the role of phase transitions in determining their properties at the individual-nanostructure level using variable-temperature scanning probe microscopy.

Hongkun Park received his B.S. degree in Chemistry from the College of Natural Sciences at Seoul National University, Korea, where he graduated summa cum laude and Valedictorian in 1990. Following a year of mandatory military service in the Republic of Korea Army, he proceeded to Stanford University, where he obtained his Ph.D. in Chemistry in 1996 under the direction of Richard N. Zare, with a thesis on photoionization dynamics of nitric oxide probed by angle- and energy-resolved photoelectron spectroscopy. He joined the faculty of the Department of Chemistry and Chemical Biology at Harvard University in 1999 after a three-year postdoctoral fellowship with Paul Alivisatos and Paul McEuen at Lawrence Berkeley National Laboratory, where his research dealt with electron transport through individual nanocrystals and nanocrystal arrays. He received the Camille and Henry Dreyfus New Faculty Award and Research Corporation Research Innovation Award in 1999, the David and Lucile Packard Foundation Fellowship for Science and Engineering in 2001, the NSF-CAREER Award and the Alfred P. Sloan Research Fellowship in 2002, the Visiting Miller Research Professorship from the University of California at Berkeley, the Ho-Am Foundation Prize in Science and the Camille Dreyfus Teacher-Scholar Award in 2003.

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Patents

Hyperion Catalysis International, Inc.

Benj — Sat, 26 Aug 2006 14:51:24 +0000

Ticker Id

Web url

http://www.hyperioncatalysis.com/

Contact Email

Short description

Street address

38 Smith Place

Zip or postal code

02138

Telephone

617.354.9678

Fax

Foundation date

Ceo, president

Number of employees

Long description

Hyperion Catalysis International, Inc. was founded in 1982 for the purpose of developing novel forms and morphologies of carbon for advanced materials and systems. Hyperion Catalysis' flagship technology is a conductive, vapor grown multi-walled carbon tube. These tubes are known commercially as FIBRIL nanotubes. Since the original discovery of carbon nanotubes in 1983, Hyperion Catalysis has devoted substantial resources to improving the technology of their manufacture and application.

Hyperion Catalysis now supplies FIBRIL (tm) nanotubes pre-mixed in a variety of plastics into a growing number of automotive and electronics industry applications. In these applications, the unique properties of nanotubes allow our customers to produce finished products whose combination of properties and performance simply cannot be equaled using other conductive materials.

Additional technologies are being developed and it is expected that they will open a wide range of exciting applications for carbon nanotubes.

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Patents

Laboratory for Multiscale Regenerative Technologies ( LMRT )

Benj — Tue, 17 Apr 2007 10:22:03 +0000

Ticker Id

Web url

http://lmrt.mit.edu/

Contact Email

Short description

Street address

Sangeeta Bhatia, M.I.T. 77 Massachusetts Ave. Bldg. E19-502d

Zip or postal code

02139

Telephone

617-324-0610 (Lab)

Fax

617-324-0740

Foundation date

Ceo, president

Number of employees

Long description

Our three main areas of research are:

Hepatic Tissue Engineering
We are interested in understanding the structure/function relationship of the liver to improve cell-based therapy for liver disease. In particular, we focus on how the microenvironment around hepatocytes (the functional cell of the liver) affects cell fate and function. We utilize microfabrication tools (methods developed to manufacture microelectronic circuits) to control and study the role of cell-cell interactions, cell-extracellular matrix interactions, soluble stimuli (e.g. O2), and three-dimensional context on hepatocyte function.

Cell-Based BioMEMS
MEMS is a term used to describe integrated microscale devices that combine electrical, mechanical, and even optical components. Since many biological species are on the same length scale as MEMS devices, the synergy of combining biological systems with MEMS (BioMEMS) can provide the basis for novel, highly instructive biological platforms. We are interested in using arrays of living cells as biosensors and as high-throughput platforms to study fundamental aspects of stem cell biology. Our repertoire of tools includes chemical, topological, fluidic, electrical, and optical manipulation of living cells on chip platforms.

Nanobiotechnology
We are involved in a multidisciplinary effort to develop nanomaterials as tools for biological studies and as multifunctional agents for cancer therapies. By bridging the unique electromagnetic properties of nanomaterials with advances in bioconjugate chemistry, photonics, and phage display we aim to develop ‘intelligent' systems for tumor therapy and biomolecular detection. Our interest centers around nanoparticles and nanoporous materials that can be designed to perform complex tasks such as: home to a tumor, sense changes in cells and tissues, enhance imaging, and trigger the release of a therapeutic payload.

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Patents

Lumarray

vinay1210 — Thu, 27 Dec 2007 13:05:24 +0000

Ticker Id

Web url

http://lumarray.com

Contact Email

zpal@lumarray.com

Short description

Street address

60 Vassar St., Cambridge

Zip or postal code

02139

Telephone

Fax

Foundation date

Ceo, president

Number of employees

Long description

Lumarray is a lithography company with a state-of-the-art-patented technology, developed at MIT, that departs from a century old tradition of conventional optics. Our technology, Zone-Plate-Array Lithography (ZPAL), integrates recent advances in microfabrication, micromechanics and fast computing to produce a lithography tool that will handle the lithographic needs of the decades to come.

We at Lumarray believe that it is time to provide a completely new way of doing lithography that will be advantageous in terms of cost and flexibility. We are working to commercialize a high-throughput maskless lithography tool that would allow for the possibility to transfer a design drawn on a computer screen directly onto a substrate. ZPAL technology is extendable to many future generations of semiconductor devices and should be capable of reaching the absolute limits of the lithographic process.

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Patents

MIT: Institute for Soldier Nanotechnologies (ISN)

Benj — Wed, 16 Aug 2006 21:54:53 +0000

Ticker Id

Web url

http://web.mit.edu/isn/

Contact Email

isn@mit.edu

Short description

Street address

Massachusetts Institute of Technology, Building NE47, 4th Floor, 77 Massachusetts Avenue

Zip or postal code

02139

Telephone

(617) 324-4700

Fax

Foundation date

Ceo, president

Number of employees

Long description

Todays dismounted infantry soldier carries a back-breaking load, usually 100-140 pounds, and still has insufficient ballistic protection, little defense against chemical and biological weapons, and too many pieces of equipment that don’t work well together. The ISNs challenge is to transform today’s cotton/nylon fatigues and bulky equipment belts to a sleek, lightweight battlesuit that provides everything from responsive armor to medical monitoring to communications and more, in one integrated system.

Nanotechnology fits into this vision in two important ways. First, it offers the potential for miniaturization, a key part of reducing weight. Todays hefty radio worn on a harness might be reduced to a button-sized tab on the collar. And a waterproof poncho could be replaced by a permanent nano-thin coating applied to everything the soldier carries. Secondly, because nanotechnology operates at length scales where classical macroscopic physics breaks down, it offers engineers the potential for creating unprecedented new materials properties and devices. Nanotechnology can solve problems that scientists have been struggling with for decades.