Nanotechnology : Washington DC

American Chemical Society (Acs)

Benj — Sun, 20 Aug 2006 14:57:21 +0000

Ticker Id

Web url

http://www.chemistry.org/

Contact Email

Short description

Street address

1155 Sixteenth Street, NW

Zip or postal code

20036

Telephone

800-227-5558 (Us), 202-872-4600 (Outside us)

Fax

202-776-8258

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Ceo, president

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The organization provides a broad range of opportunities for peer interaction and career development, regardless of professional or scientific interests. The programs and activities conducted by ACS today are the products of a tradition of excellence in meeting member needs that dates from the Society's founding in 1876.

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Bergeson & Campbell, P.C.

Benj — Sat, 02 Sep 2006 11:12:00 +0000

Ticker Id

Web url

http://www.lawbc.com/

Contact Email

Short description

Street address

1203 Nineteenth Street, N.W., Suite 300

Zip or postal code

20036

Telephone

1-202-557-3800

Fax

1-202-557-3836

Foundation date

Ceo, president

Lynn L. Bergeson

Number of employees

Long description

BERGESON & CAMPBELL, P.C.
Nanotechnology Practice

It is presumptuous for any firm to claim that it has a well defined nanotechnology practice because the practice is so young. What B&C offers is an experienced group of professionals with unique skills, capabilities, and strong relationships with the U.S. Environmental Protection Agency (EPA), the National Institute for Occupational Safety and Health (NIOSH), and the Occupational Safety and Health Administration (OSHA) decision-makers, all of which are essential for the chemical community to navigate around the challenges and benefits posed by current uses of engineered nanoscale materials and the emerging commercialization of nanotechnology.

B&C has made a concerted effort to be in the forefront of the science policy debate involving nanotechnology and other emerging technologies. B&C professionals have participated in all Foresight and Governance Project Dialogues on nanotechnology. Presently, Lynn Bergeson serves on the Steering Committee of the American National Standards Institute Nanotechnology Standards Panel (ANSI-NSP), which is seeking to coordinate the development of voluntary consensus standards relating to nanotechnology. As long-time sponsors of the American Chemistry Council (ACC) Global Chemical Regulations Conference, B&C is presenting in March 2005 a panel discussion on nanotechnology and regulatory review initiatives. Ms. Bergeson is also a member of the Converging Technologies Bar Association (CTBA), which is very active in developing legal and policy issues pertinent to emerging technologies. Finally, B&C’s article, “Reading the Small Print,” which appeared in the March/April 2004 issue of the Environmental Law Institute’s The Environmental Forum, has received praise for flagging significant regulatory and policy issues pertinent to nanotechnology and nanoscale materials.

Our attorneys are well versed in the legal authorities, administrative programs, and regulatory options that EPA and other government agencies, including NIOSH, OSHA, and the Food and Drug Administration (FDA), are now exploring to address the potential risks posed by the use of engineered nanomaterials, the commercialization of nanotechnology, and the convergence of other emerging technologies.

Experience with other legal authorities is also needed, however, and B&C is uniquely qualified to offer these diverse skills. For example, B&C professionals have long worked with EPA’s Office of Pollution Prevention and Toxics staff on Toxic Substances Control Act (TSCA) Inventory and nomenclature issues. We are now working with clients on precisely these issues and on EPA’s continuing revisions of the TSCA regulatory framework, as it relates to nanomaterials and nanostructures that consist of chemical substances. B&C professionals have also long worked with NIOSH on a wide range of issues. Presently, B&C is working with NIOSH on its review of titanium dioxide (TiO2) and, in particular, its hazard assessment of TiO2 in pigment grade and ultra fine particle form. NIOSH intends to release soon a Comprehensive Intelligence Bulletin on TiO2 which, in part, is expected to be pertinent to its broader review of hazards posed by nanoscale materials.

B&C professionals also work closely with several FDA offices. Michael F. Cole is a distinguished FDA practitioner with three decades of experience with FDA obtaining FDA approval for substances used in packaging materials and food processing equipment, preparing Drug Master Files, counseling on the need to submit, and the strategy for, obtaining clearances for device Premarket Notification and Premarket Approval Applications, counseling on medical device classification matters, defending cosmetic ingredient use, and related topics.

Similarly, B&C has significant experience in counseling clients and conducting advocacy initiatives with the National Toxicology Program (NTP) and has worked for years with scientists inside and outside of NTP on science policy issues involving testing protocols, the development of analytical methods, and related topics. B&C represents many companies and trade organizations that have disputed or are in the process of disputing the findings of an NTP study. Our assistance in this regard has consisted of marshaling the technical resources necessary to launch a comprehensive review of the findings, drafting the advocacy documents necessary to support such an effort, and representing our clients in discussions with NTP staff. Given NTP’s current research initiatives involving nanoscale materials, this experience is invaluable.

We also work closely with companies and chemical testing consortia to ensure that NTP’s selection of chemicals, protocols used once a chemical has been nominated for chemical testing, and the technical conclusions and inferences drawn from the test results are presented in a fair and technically defensible way. B&C offers clients an NTP tracking system that advises clients of the status of NTP’s chemical testing initiatives with respect to particular chemical compounds. This tracking system allows companies an opportunity proactively to participate in the chemical testing process. Doing so helps blunt the possibility for erroneous test results, and hence minimizes the possibility that ill-conceived conclusions will be drawn with respect to test chemicals.

B&C routinely counsels clients on a wide variety of matters under the Occupational Safety and Health Act. B&C’s representations include assisting many chemical consortia in the development of American Conference of Governmental Industrial Hygienists’ threshold limit values applicable to, among other chemicals, carbon disulfide, phenol, ethylene glycol, and certain nickel compounds. We have worked on the development of many permissible exposure limits and routinely offer regulatory counseling and enforcement defense services.

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George Washington University: Wagner lab

Benj — Fri, 25 Aug 2006 13:25:19 +0000

Ticker Id

Web url

http://home.gwu.edu/~wagnerm/index.html

Contact Email

Short description

Street address

2121 Eye Street, N.W.

Zip or postal code

20052

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Fax

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Ceo, president

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These materials can have vastly enhanced properties over their bulk counterparts because of their high surface area to volume ratio and quantum effects due to electronic confinement. In addition to our interest in their intrinsic properties, we also utilize them as precursors to metastable and nanostructured materials as well as components of composites.

Currently, we have three main project areas, all well supported by external funding, the synthesis of nanoscale materials by alkalide reduction, development of magnetic refrigerants for ambient temperature applications and the development of improved Li-ion battery electrode materials. Follow the links to the left to meet the members of the lab, learn about the projects, take a virtual tour of the labs and see pictures from some of the meetings/events we have attended.

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Greater Washington Nanotech Alliance

Benj — Fri, 01 Sep 2006 19:03:16 +0000

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Web url

http://www.nanotech-alliance.org/

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Intertech-Pira conference : Regulations for Nanotechnology in Consumer Products

Benj — Fri, 15 Dec 2006 16:17:02 +0000

Short description

Assessing the future regulatory landscape for nanotechnology in consumer products.
Two day Intertech-Pira conference plus workshop.

Long description

Currently, there are over 400 consumer products on the market today that use nanotechnology. In 2005, emerging nanotechnology was incorporated into roughly US$30 billion in global manufactured goods. By 2014, that number is expected to increase to US$2.6 trillion, or about 15% of global output.*

Industries ranging from food and beverage to pharmaceutical have already allocated large resources into R&D to find out how nanotechnology can benefit them. Emerging start-ups with innovative nanotechnology patents are drawing investors at record speed. Would new regulations choke these creative companies while allowing larger, better funded firms to rein in competition?

This program will bring together regulators from various impacted industries combined with views from multiple industries. Scientific findings will be presented including the latest nanotoxicology reports and global regulation initiatives from Asia and the EU for nanotechnology leaders to discuss and present suggestions on where consistency and compromise is needed.

Intertech-Pira is an industry leader in bringing you the latest breakthroughs in nanotechnology and regulations. Join other industry leaders at this innovative conference as we bring these two forward looking topics together for the first time!

*Source: Lux Research

Event precise location and contact information

Washington Marriott,
Washington, DC, US

Heath Clendenning, Conference Manager
T: +1 207 781 9629 F:
E: heath.clendenning@pira-international.com

Chandra Leister, Conference Coordinator
T: +1 207 781 9602 F:
E: chandra.leister@pira-international.com

Lisa C Valentine,
T: 00 1 207 781 9627 F:
E: lisa.valentine@pira-international.com

Web site Url link

http://www.intertechpira.com/events.asp?step=2&eventID=313968F1012BF333BC0D1012BF323A94E1012BF|2CB9BF|1CA700

Web site Url text

Intertechpira

Nanomaterials in Biology and Medicine: Promises and Perils

Fri, 23 Mar 2007 16:34:54 +0000

Short description

The National Academy of Sciences will host the 7th Annual Sackler Lecture, "Nanoscience and Nanotechnology: A Portrait in Early Adolescence," delivered by George Whitesides at 6 p.m. on Tuesday, April 10. Dr. Whitesides is a member of the National Academy of Sciences and the National Academy of Engineering, and is the chair of the Committee on Science, Engineering, and Public Policy. He was awarded the National Medal of Science in 1998 and is currently the Woodford L. and Ann A. Flowers University Professor at Harvard University.

Long description

The public is cordially invited to attend this lecture, which is free. It will take place in the NAS auditorium; a poster session and reception precede the lecture from 5 p.m. to 6 p.m. RSVP online at http://www.nasonline.org/SACKLER_Lecture_2007.

Dr. Whitesides' lecture is presented in connection with the Sackler Colloquium Nanomaterials in Biology and Medicine: Promises and Perils, which will take place on April 10-11. At this event researchers will discuss new ways to create functional nanomaterials in biology, challenges involved in bringing these technologies to the consumer, and related societal and ethical concerns. A program, list of speakers, and registration information for the 2-day colloquium are available online at www.nasonline.org/Sackler_nanoprobes.

There has been an explosive development in materials development which uses nanoscale materials to probe biological processes and diagnose medical conditions (such as tumor detection). There are unique aspects of nanoscale materials which allow them to preferentially penetrate and be retained by biological cells and tissue and there have been developments in new ways to detect and image and nanomaterials in cells and biological tissue. Further, the size scale of nanoprobes will allow us to build complexity into nanoprobes which allow them to be multi-functional, with both diagnostic and drug delivery. However, we must also be aware that these nanomaterials can have drastically different behavior in biological tissue than larger scale materials of exactly the same composition, so issues of societal and ethical outcomes must also be considered. The colloquium will be structured to address graduate students, postdoctoral fellows, directors of public granting agencies, and policy makers.

Event precise location and contact information

National Academy of Sciences Auditorium
1. Take Metro's Orange or BLue Line to the Foggy Bottom-GWU station.
2. Turn RIGHT on to 23rd Street N.W. when you exit the station.
3. Walk SOUTH on 23rd Street N.W. for approximately 7 blocks.
4. Turn LEFT on to C Street N.W. (after the State Department).
5. Cross 22nd Street N.W. The next building on your right will be 2100 C St. N.W.

sackler@nas.edu

Web site Url link

http://www.nasonline.org/Sackler_nanoprobes

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Nanomaterials in Biology and Medicine: Promises and Perils

Nanoverse LLC

Benj — Wed, 16 Aug 2006 17:50:52 +0000

Ticker Id

Web url

http://www.nanoverse.net/

Contact Email

ContactUs@nanoverse.net

Short description

Street address

P.O. Box 58153, Watergate Station

Zip or postal code

20037

Telephone

Fax

Foundation date

Ceo, president

Richard Smith / Mark Menna

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Nanoverse's vision is to solve real-life problems (primarily in the fields of health, energy, and homeland defense) by uncovering novel nano- and near-nanotechnologies and creating profitable companies around them. It's objectives are to convert nanoscience projects into products and industries; to apply expertise and network connections to nanotech development and commercialization. Our expertise includes technology evaluation, ideation and product development, business planning, partnering with government and industry programs, and developing public and private capital. Nanoverse will also host the nanotechnology component of the US Pavilion at the World Expo in Nagoya, Aichi, Japan in 2005.

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Nuclear Solutions, Inc.

Benj — Thu, 17 Aug 2006 17:34:36 +0000

Ticker Id

Web url

http://www.nuclearsolutions.com/

Contact Email

info@nuclearsolutions.com

Short description

Street address

5505 Connecticut Ave NW #191

Zip or postal code

20015

Telephone

202-787-1951

Fax

202-318-2487

Foundation date

Ceo, president

Number of employees

Long description

At nuclear solutions we believe in the power of unbridled creative thinking coupled with pragmatic expectations. This elemental principle combined with a management and technical team processing a broad, interdisciplinary scientific and business background naturally yields new ideas and ways to solve old problems and create new opportunities.

At nuclear solutions, our goal is not only to improve existing nuclear technologies, but also to advance the state of the art in nuclear science in order to realize the benefits of safe, environmentally friendly nuclear energy while eliminating the liabilities.

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Project on Emerging Nanotechnologies

Benj — Thu, 31 Aug 2006 12:03:28 +0000

Ticker Id

Web url

http://www.nanotechproject.com/

Contact Email

Short description

Street address

Woodrow Wilson International Center for Scholars, Ronald Reagan Building and International Trade Center, One Woodrow Wilson Plaza, 1300 Pennsylvania Ave.

Zip or postal code

20004-3027

Telephone

(202) 691-4282

Fax

(202) 691-4001

Foundation date

Ceo, president

Number of employees

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Nanotechnologies are hailed by many as the next industrial revolution. They promise to change everything from the cars we drive to the clothes we wear, from the medical treatments our doctors can offer to our energy sources and workplaces. Although focused on the very small, nanotechnologies offer tremendous potential benefits. From new cancer therapies to pollution-eating compounds, from more durable consumer products to detectors for biohazards like anthrax, from novel foods to more efficient solar cells, nanotechnologies are changing the way people think about the future.

The Project on Emerging Nanotechnologies collaborates with researchers, government, industry, NGOs, policymakers, and others to look long term, to identify gaps in knowledge and regulatory processes, and to develop strategies for closing them. The Project will provide independent, objective knowledge and analysis that can inform critical decisions affecting the development and commercialization of nanotechnologies.

Our goal is to inform the debate and to create an active public and policy dialogue. It is not an advocate either for, or against, particular nanotechnologies. We seek to ensure that as these technologies are developed, potential human health and environmental risks are anticipated, properly understood, and effectively managed.

All research results, reports, and the outcomes of our meetings and programs are made widely available through publications and over the web. We include a wide variety of stakeholders, both domestically and internationally, in our work.

We also are committed to engaging a new generation of young people interested in working at the interface of public policy and nanoscience and nanoengineering. We run an active program with university researchers, educators, and students to further that objective.

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Patents

Roylance, Abrams, Berdo & Goodman

Benj — Sat, 19 Aug 2006 15:11:52 +0000

Ticker Id

Web url

http://www.roylance.com/

Contact Email

info@roylance.com

Short description

Street address

1300 19th Street, N.W. Suite 600

Zip or postal code

20036

Telephone

+1-202-659-9076

Fax

+1-202-659-9344

Foundation date

Ceo, president

Number of employees

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Founded in 1954, attorneys of Roylance, Abrams, Berdo & Goodman, L.L.P. specialize in intellectual property law including a wide range of patent, trademark, copyright, unfair competition and trade secret matters for clients of all sizes. We provide a full range of representation in these areas from litigation, acquisition, and licensing to counseling and advice both nationally and in foreign countries. Our nanotech practice group actively participates in various conferences and seminars to stay abreast of the latest technical and legal developments.

With techniques proven through experience, the firm specializes in post-grant proceedings before the US Patent and Trademark Office -- reexamination of competitor patents, reissue of client patents to strengthen the patent for licensing and litigation, and interferences that establish the first inventor between competing applications.

Many of our attorneys have been patent and trademark examiners from the U.S. Patent and Trademark Office. That experience provides a unique insight into workings of the PTO and the requirements of examiners for an efficient prosecution of new applications. Our close proximity to the U.S. Patent and Trademark Office lets us stay in touch with the latest developments at the PTO and allows us to conduct personal interviews with examiners.

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SHORT COURSE: Communicating Risk about Nanotechnology in the 21st Century

Thu, 15 Feb 2007 17:35:41 +0000

Short description

INSTRUCTOR:Prof. David Berube, University of South Carolina

This course will examine some of the unique features of applied nanoscience and the research on communicating risk which is relevant to developing a communication algorithm for different audiences. The course rewrites risk management formulae to compensate for "new" media (internet based) and for some of the societal concerns expressed in public outreach including but not limited to environmental health and safety.

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Event precise location and contact information

Web site Url link

http://www.rarecor.com/nanotechnology_short_course_risk_communication_berube.shtml

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RARE Corporation

The Acta Group, L.L.C.

Benj — Wed, 06 Dec 2006 11:18:25 +0000

Ticker Id

Web url

http://www.actagroup.com/

Contact Email

Short description

Street address

1203 Nineteenth street, NW, Suite 300

Zip or postal code

20036-2401

Telephone

202/266-5020

Fax

202/557-3836

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Ceo, president

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Acta and Acta EU manage products from concept to approval, utilizing the skills and experience of professionals who have worked in the specific product areas in government and industry. Acta and Acta EU represent the following disciplines:

IN FOCUS :
FDA Practice

* Regulatory Affairs: Professionals skilled in the requirements for approval, including the content and form of submissions, and experienced in overall project management.

* Toxicologists: Skilled in conducting literature searches, technical reviews, in-depth data reviews, study design and management, risk assessments, and exposure assessments for products regulated by the United States Environmental Protection Agency (EPA), United States Department of Agriculture (USDA), and Food and Drug Administration (FDA).

* Government Affairs: Experts skilled in the workings of the regulatory agencies and adept at involving the executive and legislative branches of government, when necessary, to resolve policy issues.

Acta and Acta EU professionals have experience in regulations affecting chemical product approvals under North American (USA, Canada, and Mexico), European Union, South American, Asian, and Pacific Rim regulatory programs. They regularly track significant legislative, administrative, and scientific initiatives that relate to the business of clients marketing chemicals and medical products for multiple uses.

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U.S. Environmental Protection Agency : Nanotechnology ( EPA )

Benj — Sat, 23 Jun 2007 09:36:12 +0000

Ticker Id

Web url

http://es.epa.gov/ncer/nano/

Contact Email

Short description

Street address

Ariel Rios Building 1200 Pennsylvania Avenue, NW

Zip or postal code

20460

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Fax

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Ceo, president

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EPA has taken a leadership role in planning research directions for the environmental applications and implications of nanotechnology - through its own research programs and participation in the interagency Nanoscale Science, Engineering, and Technology subcommittee of the White House Office of Science and Technology Policy, National Science and Technology Council.

EPA’s nanotechnology efforts conducted by the Office of Research and Development (ORD) include the following:

ORD’s National Center for Environmental Research, through the Science to Achieve Results program, EPA has funded 32 research grants for more than $11 million in the applications of nanotechnology to protect the environment including the following: development of low-cost, rapid, and simplified methods of removing toxic contaminants from surface water; new sensors that are more sensitive for measuring pollutants; green manufacturing of nanomaterials; and , more efficient, selective catalysts. At least one project is moving rapidly toward commercial application - zero-valent iron nanoparticles have been modified so that they can be used to reduce chlorinated organics in contaminated ground-water sites. http://www.epa.gov/ncer

Twelve recently selected research projects focus on studying the possible harmful effects of manufactured nanomaterials, i.e., toxicity, fate, transport and transformation, and exposure and bioaccumulation. A new research solicitation for 2005 was announced collaboration with two other federal agencies to study the health and environmental effects of manufactured nanomaterials.

Through its Small Business Innovation Research Program , EPA awarded contracts to over 20 small companies to develop and commercialize nanomaterials and clean technologies. Recently, an SBIR company demonstrated an activated carbon nanofiber filter with large surface area that more efficiently removes volatile organic compounds and particles smaller than 3 μm from engine exhaust, power generators, and indoor air.

A number of research projects in ORD laboratories are being conducted including the following: nanostructured photocatalysts as green alternatives to oxygenation of hydrocarbons; using nanomaterials as adsorbents, membranes and catalysts to control air pollution and emissions; and, the effects of ultrafine particulate matter that could help inform the research on manufactured nanomaterials.

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Patents

US Naval Research Lab: Nanoscience and technology

Benj — Fri, 18 Aug 2006 16:59:43 +0000

Ticker Id

Web url

http://www.nanosra.nrl.navy.mil/

Contact Email

Short description

Street address

US Naval Research Lab, Code 6100, 4555 Overlook Ave., S.W.

Zip or postal code

20375

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Fax

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Ceo, president

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Recognized Applications of Nanoscience:

-Ultrasmall, highly parallel, computers with multi-teraflop speed
-Image information processors, e.g., extraction and recognition
-Low-power personal and autonomous communication and computation devices
-high-density information storage devices, e.g., terabit/cm2 nonvolatile memory
-Lasers and detectors for weapons and countermeasures
-Optical (infrared, visible, ultraviolet) sensors for improved surveillance and targeting
-Integrated sensor suites for chemical and biological agent detection
-Catalysts for enhancing and controlling energetic reactions
-Synthesis of new compounds (e.g., narrow-bandgap materials)
-Designer materials with combinations of properties that do not currently exist

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Patents

USISTF : United States-Israel Science and Technology Foundation

Benj — Thu, 17 Aug 2006 17:08:10 +0000

Ticker Id

Web url

http://www.usistf.org/

Contact Email

Short description

Street address

2000 L St. NW, Suite 800

Zip or postal code

20036

Telephone

202.419.0430

Fax

202.419.0435

Foundation date

Ceo, president

Number of employees

Long description

In March 2004, the USISTF convened a Nanotechnology Roundtable that brought together US and Israeli representatives from government, academia and the private sector to identify factors necessary to set the climateУ” for partnership and business creation.

The Nanotechnology Roundtable will identify factors necessary to set the climateУ” for partnership and business creation. Critical to this concept is the need for strategic plan-ning with a focused effort. Therefore, emphasis will be placed on determining measures necessary to promote the development of infrastructure components, such as government, financial, business, scientific and academic areas that are needed to catalyze growth in the nanotechnology field between U.S. and Israel.

Specific recommendations will be developed for programmatic activities consistent with the mission and objectives of the US-Israel Science and Technology Commission and Foundation including processes and approaches for business creation. Roundtable dis-cussion will provide the basis for developing a clear plan of action with a set of well-defined priorities and strategies. Participants will consider the following four critical questions in developing a viable nanotechnology initiative.

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Patents

Wilmer Cutler Pickering Hale and Dorr LLP

Benj — Tue, 29 Aug 2006 13:29:02 +0000

Ticker Id

Web url

http://WilmerHale.com/

Contact Email

Short description

Street address

1875 Pennsylvania Avenue, NW

Zip or postal code

20006

Telephone

+1 202 663 6000

Fax

+1 202 663 6363

Foundation date

Ceo, president

Number of employees

Long description

Today, businesses face greater scrutiny and more "bet the company" issues than ever before. With a practice that offers unparalleled representation across a comprehensive range of practice areas, we have the ability to anticipate obstacles, seize opportunities and get the case resolved or the deal done—and the experience and know-how to prevent it from being undone.

We are more than 1,000 lawyers strong, with offices in 14 cities in the United States, Europe and Asia. Our practice includes 350 litigators with unmatched trial, appellate, Supreme Court and arbitration experience; preeminent regulatory practices in antitrust, communications, FDA, financial services, securities, trade and other areas including over 100 lawyers who have held high-level government positions; an acclaimed intellectual property practice enriched by the expertise of nearly 100 attorneys and patent agents who hold scientific or technical degrees; more than 250 seasoned corporate transactional lawyers and business counselors; extensive international capabilities and cross-border experience; and hundreds of other lawyers who focus on bankruptcy, environmental, labor and employment, private client, real estate and tax matters.

Wilmer Cutler Pickering Hale and Dorr LLP was formed in May 2004 through the merger of Hale and Dorr LLP and Wilmer Cutler Pickering LLP. The two firms brought more than 125 years of distinguished history as well as complementary strengths to our new firm, which has an even broader spectrum of top-ranked practices. To each practice, we bring outstanding reputations for quality, excellence and service to clients.

Our firm fosters a collaborative culture that allows each lawyer to draw freely on the expertise and time of others to serve any client. We balance our proud heritage and thorough understanding of the law with an innovative and entrepreneurial spirit. Our practice is constantly evolving in response to our clients’ needs, the demands of the market and the emergence of new technologies.

We have a rich heritage of commitment to public service and the causes of justice and fairness. With a history that goes back to the foundation of legal aid work early in the 20th century, we have consistently distinguished ourselves as leaders in pro bono representation. Many of our lawyers have played, and continue to play, prominent roles in public service activities of national and international importance—from counseling US presidents to opposing racial discrimination and fighting apartheid.

Most importantly, our firm stands for a steadfast commitment to the highest standards in everything we do—a commitment reflected in the continued success of our clients across the globe.