Nanotechnology : Microfluidics

New Platform for Microfluidics Research

micronit — Tue, 01 Jul 2008 12:14:44 +0100

Short description

Micronit Microfluidics today announced a new lab-on-a-chip platform named “Fluidic Connect”. The platform enables researchers to create their own lab-on-a-chip setup in just a few minutes of time.

Article body

Micronit launches easy-to-use and affordable lab-on-a-chip platform named “Fluidic Connect”

Enschede, The Netherlands, July 1st, 2008 – Micronit Microfluidics today announced a new lab-on-a-chip platform named “Fluidic Connect”. The platform enables researchers to create their own lab-on-a-chip setup in just a few minutes of time.

Fluidic Connect offers a solution for two major problems in the use of lab-on-a-chip, namely integration with existing equipment, and replacement of microfluidic chips. “Fluidic Connect allows the use of standard laboratory equipment in combination with microfluidic chips”, explains Ronny van ‘t Oever, CTO and co-founder of Micronit. “With Fluidic Connect, a larger chip area can be detected with a microscope objective. The user-friendly chip cartridge with the size of a microscope slide enables an easy chip connection. The chip holder guarantees a leak-free connection up to 100 bars and 100 degrees Celsius.”

Within the lab-on-a-chip platform, different microfluidic chips are available off-the-shelf, such as microreactors, micromixers and cross channel chips. These chips are all compatible with the Fluidic Connect 4515 chip holder and the connection kits. Clients are also free to design their own chips that are compatible with the platform. For customized chips with integrated electrodes, Micronit recently launched easy-to-use electrical connections, also compatible with Fluidic Connect.

Fluidic Connect is a modular product that can be integrated as a building block in a laboratory system or setup. According to Van ‘t Oever, it can be easily adapted to specific applications, depending on the relative importance of requirements like low dead volume, pressure and temperature range. He concludes: “Fluidic Connect enables researchers to significantly reduce the time to do their analysis. And above all, it reduces their frustration when creating and connecting a lab-on-a-chip setup.”

Source information

Micronit Microfluidics
Ms. M. Pelle
marketing@micronit.com
+31 53 850 68 67

Source title

Source Url

http://www.micronit.com

Clearing the US and EU Regulatory Path to Product Approval – “What Similarities and Differences Exist and How Can Companies Mana

aneeshasks — Mon, 24 Mar 2008 19:46:42 +0000

Short description

Clearing the US and EU Regulatory Path to Product Approval – “What Similarities and Differences Exist and How Can Companies Manage the Hurdles?”

Learn how to navigate through the complexities and policy changes that biotech and nanotech products face today. Expert advice and case studies will provide valuable lessons on how policy and regulation is influencing technology in the US and EU and what companies can do to save time and cost throughout the process. Do regulatory agencies have the legal authority to make judgments on nanomaterials? Are they ready for this responsibility?

Long description

Clearing the US and EU Regulatory Path to Product Approval – “What Similarities and Differences Exist and How Can Companies Manage the Hurdles?”

Featured Speakers:

Kjell Srandberg, M.D., Ph.D.
Advisory Board Chairman NDA,
Regulatory Consultant Service AB,
Former Director General of the Swedish Medical Products Agency & member of CPMP

Ricardo Carvajal,
Esq. Of Counsel, Hyman, Phelps & McNamara, P.C.,
former – FDA Counsel

Moderator: Michael A. Swit, Esq.
Vice President, The Weinberg Group

Place: Morrison & Foerster, 12531 High Bluff Drive, Suite 100, San Diego, California 92130

Date: Thursday, April 10, 2008

Time: 5:30 pm - 8:30 pm
5:30pm Reception and networking
6:30pm Program begins

Event precise location and contact information

Place: Morrison & Foerster, 12531 High Bluff Drive, Suite 100, San Diego, California 92130

Web site Url link

www.nanobionexus.org

Web site Url text

Sigma-Aldrich Corporation

dgaige — Tue, 26 Feb 2008 15:37:53 +0000

Ticker Id

Web url

http://www2.sigmaaldrich.com/suite7/Area_of_Interest/Chemistry/Materials_Science/Nanotechnology/Nanotech_Intro.html?cm_mmc=NanoVIP-_-affiliate-_-link-_-link

Contact Email

ContactSigma-Aldrich@sial.com

Short description

Street address

3050 Spruce Street

Zip or postal code

63103

Telephone

(800) 521-8956

Fax

(800) 325-5052

Foundation date

Ceo, president

Jai Nagarkatti

Number of employees

Long description

Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. We have customers in life science companies, university and government institutions, hospitals and in industry. Sigma-Aldrich operates in 36 countries and has over 7,600 employees providing excellent service worldwide.

Additional Commentaries and remarks

Patents

Dolomite's Microfluidic Reactor Chip Enables Powerful Flow Chemistry Technology

energi — Wed, 16 Jan 2008 18:41:05 +0000

Short description

Microfluidic flow reactor modules supplied by Dolomite, enable the fast and efficient processing of chemicals for test and analysis. Used within Syrris’s flow reactor instruments, this technology is starting to have a significant impact on companies involved in such areas as drug discovery, DNA analysis and forensic science, by greatly accelerating their research.

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Dolomite has announced that its microfluidic device fabrication expertise is being used by automated laboratory equipment specialist, Syrris Ltd, within its novel range of flow reactor instruments. These microfluidic flow reactor modules supplied by Dolomite, enable the fast and efficient processing of chemicals for test and analysis. Used within Syrris’s flow reactor instruments, this technology is starting to have a significant impact on companies involved in such areas as drug discovery, DNA analysis and forensic science, by greatly accelerating their research.

Dolomite is a leader in Microfluidics, also known as ‘lab on a chip'. This is an exciting new field of science and engineering that enables very small-scale fluid control and analysis, allowing instrument manufacturers to develop smaller, more cost-effective and more powerful systems. With lab-on-a-chip technology, entire complex chemical management and analysis systems are created in a microfluidic chip and interfaced with, for example, electronic and optical detection systems.

“Flow chemistry in microreactors often happens much faster than reactions in a bulk vessel, as a result of being able to run at elevated temperature,” said Philip Homewood, Engineering Manager at Dolomite. “It is also possible to improve product yield because the reaction conditions in a flow microreactor are closer to ideal conditions in terms of temperature and input reagent concentration. This technology is bringing a lot of important new benefits to the life science community and is having a major influence on the future of scientific instrument design and modern chemistry.”

UK company Syrris specialises in flow reactor tools for enhancing the productivity of R&D chemists. Their market-leading product Africa, a modular system for reaction optimisation, reduces the time taken to develop, synthesize, work-up and analyse a chemical entity. In laboratories around the world the Africa system is speeding up the drug discovery process.

“The microfluidic reactor chips from Dolomite are a critical component of the Africa system,” said Mike Hawes, Marketing Manager at Syrris. “Mixing in a batch reactor is quite random whereas in a microfluidic flow reactor it is far more uniform. For some processes like nano-particle manufacturing and crystallisation processes, the nano-particles or crystals end up being much more uniform in comparison to an equivalent batch reactor process. This important benefit, along with the speed and control achievable with this technology, is enabling us to help scientists accelerate their research and achieve more reproducible results.”

Key to the fabrication of these microfluidic devices is the use of microfabrication techniques capable of creating microchannels and complex structures in materials suitable for handling chemicals without being chemically attacked. Dolomite has expertise in the fabrication of devices in one such inert material, glass. “Glass is susceptible to breakage and chipping making it a difficult material to handle,” said Phil Homewood. “This is one of the main reasons why there are so few suppliers of glass microfluidic devices in the world.”

One of the challenges in the design and manufacture of microreactor chips includes getting a sufficient reaction volume. Most chips are less than 100microlitres in volume. To achieve greater volumes, Dolomite etches channels in both glass layers. The micron-sized features on the two patterned layers are aligned, before being bought into optical contact and thermally bonded to create the final device. “Recently we have developed a technique that enables us to align features as small as 5 microns wide”, said Phil Homewood. “Another challenge was the design of the mixing junction to make sure the diffusional mixing was fast enough. This was achieved by having a narrow channel after the mixing junction to keep the diffusion distance low. Also before the mixing junction, one of the input streams was split onto two streams and combined either side of the other input stream. The effect is that the diffusion distance is reduced by a factor of two. This reduces diffusional mixing time by a factor of four. Although each chip is only 28x90mm in size it has between 1.8 - 2.5m of reaction channel.”

About Dolomite
Established in 2005 as the world’s first microfluidic application centre, Dolomite is focussed on working with customers to turn their concepts for microfluidic applications into reality. With an in-depth understanding of chemistry and the life sciences, expertise in microfabrication and microfluidics, together with instrument design and development capabilities, Dolomite is enabling some of the world’s top providers in fields as diverse as environmental monitoring, drug discovery and forensic science to deliver microfluidic systems to the market place. To find out more about Dolomite, please visit – www.dolomite-microfluidics.com.
About Syrris
Syrris Ltd is a market leader in the field of microreactors and productivity improvement for R&D chemistry. Syrris specialises in flow reactors, including FRX: a low cost flow chemistry system and the Africa, a modular system for reaction optimisation that will ultimately reduce the time taken to develop, synthesize, screen and review a chemical entity, thus vastly speeding up the drug discovery process. For further information about Syrris, please visit – www.syrris.com.

Source information

Contact:
Dolomite Contact: Dr Gillian Davis, Commercial Director
Tel: +44 1763 242491
e-mail: sales@dolomite-microfluidics.com

Syrris Contact: Mike Hawes, Marketing Manager
Tel: +44 (0)1763 242 555
e-mail: mike.hawes@syrris.com

Media Contact: Richard Blackburn, Energi Technical Limited
Tel: +44 1603 278228
e-mail: richard@energi-tech.co.uk

Source title

Dolomite Microfluidics

Source Url

http://www.dolomite-microfluidics.com

Dutch Wafers to Study Early Universe

micronit — Mon, 17 Dec 2007 11:25:47 +0000

Short description

Cosine Research (cosine) and Micronit Microfluidics (Micronit) are proud to announce their cooperation in an X-ray telescope project for the European Space Agency (ESA).

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Micronit Microfluidics and Cosine Research Develop Next-Generation ESA X-ray Telescope

Cosine Research (cosine) and Micronit Microfluidics (Micronit) are proud to announce their cooperation in an X-ray telescope project for the European Space Agency (ESA). The collaborative project concerns the development of a new type of lens for the observation of X-ray radiation from the universe. This new type of lens is much lighter than comparable lenses and can therefore be more economically sent into outer space. Cosine leads the international consortium of companies and knowledge institutes that include Micronit and the Netherlands Institute for Space Research (SRON).

The X-ray telescope being developed for XEUS is made from silicon wafers. These wafers are commonly used in the electronics industry to make electronic chips, and can be bonded together to form an X-ray lens. For an X-ray lens, a large surface is needed, but a stack of precisely structured wafers can have the same effect. The manufacture and assembly of silicon wafers is a complicated job requiring precision of one ten-thousandth of a millimetre. Micronit will manufacture the wafers to these precise dimensions by using special processing techniques and equipment. Cosine will then assemble the wafers in such way that a light-weight, precise, and robust lens is created that can survive the harsh conditions of outer space.

The X-ray lens is being developed for ESA’s proposed XEUS satellite. Recently, XEUS was selected as one of the candidates for the Cosmic Vision program, a plan for scientific satellites that will be launched by ESA between 2015 and 2025. XEUS is a next-generation telescope that will study the fundamental laws and the origin of the universe. The origin of black holes, the evolution of galaxies, the development of structures on cosmic level and extreme gravity under extreme conditions are just a few examples of the things that can be studied with XEUS. The selection for the Cosmic Vision program increases the chance that the X-ray lens developed by cosine and Micronit will be used in future missions.

Ronny van ‘t Oever, co-founder and CTO of Micronit: “It is essential that the silicon wafers are processed with a very high accuracy. We are proud that our etching and bonding techniques have been chosen as the best alternatives for the project. We are very glad to have cosine as our partner. Both our companies develop solutions for high-tech scientific problems, and this gives a good match.”

For Marco Beijersbergen, founder and manager of cosine, this contract is an important step. In the beginning of his company, he worked with ESTEC, the technology centre of ESA in Noordwijk (NL). In that time, he stood at the cradle of the design of the XEUS telescope and was one of the co-inventors of the technology. “The first job we won with cosine was the development of the XEUS-technology we invented with ESTEC. Meanwhile, cosine does a lot more, but the design of XEUS and the development of this technology is still an important activity. The assignment of this important job and the selection for the Cosmic Vision program is the crowning glory of many years of research. The cooperation between cosine and Micronit dates from the first phase of this development in 2001. The cooperation is now considerably strengthened with this assignment.”

Source information

For more information, please contact:

Mr. M. Beijersbergen, manager of cosine
E-mail: m.beijersbergen@cosine.nl
Phone: +31 71 528 49 64 or +31 623 35 11 70

Ms. M. Pelle, Marketing & PR of Micronit Microfluidics BV
E-mail: marketing@micronit.com
Phone: +31 53 850 68 67

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Dolomite Launches The World's First Microfluidic Edge Connector

Wed, 07 Nov 2007 11:47:50 +0000

Short description

New microfluidic connector enables systems development and improved fluid flow.

Article body

New microfluidic connector enables systems development and improved fluid flow.

Leading microfluidic development company Dolomite have announced the release of a new microfluidic connector that will enable engineers and scientists to interface to microfluidic chips, helping them develop and manufacture microfluidic based fluid control systems more easily. The initial design of the in-line connector has four ports and is engineered to connect easily and perform reliably.

"Microfluidic chips have had a big impact on instrument design and development," said Mark Gilligan, Managing Director. "They enable small scale fluid control and analysis, allowing manufacturers to develop smaller, more cost-effective and more powerful systems. However, connecting and interfacing to these devices is a challenge in itself. We are confident that the new connectors that we are introducing to this market will be well received and will help reaffirm Dolomite’s commitment to developing products that enable engineers and scientists to apply microfluidic technology to their systems and products."

The new Dolomite microfluidic connector removes the need for expensive drilled holes in the chip by incorporating the holes into the actual chip fabrication process. Using this connector fluid flow is improved, as the fluid paths are straight-in rather than perpendicular, providing a smooth linear pathway. The standard version of the new connector is a fluidic bus with four fluid input/output ports on a single integrated connector to make chip connection and disconnection simple and fast.

"This device will benefit a broad range of industries," said Mark Gilligan. "Microfluidic devices are now being used in patient care systems, DNA testing, air pollution monitoring, fuel cell technology and drug development. It's very much an emerging technology with a huge potential and we already have a lot of interest in this device and the benefits that it will bring."

Dolomite has established itself as a leader in the field of microfluidics, working in chip design, chip fabrication, fluidic interfaces, flow cells, pumps, valves, detectors and integrated systems. They are also equipped with rapid prototyping facilities for the design and fabrication of glass and quartz devices and can provide low or medium volume production in glass or quartz and high volume production in polymers.

Microfluidic devices are developed using microfabrication techniques capable of creating microchannels and complex structures in the glass. The main fabrication processes are photolithography, wet etching of microchannel structures, micro-drilling of fluid ports, thermal bonding and surface modification. Dolomite are also able to undertake traditional precision glass processing techniques such as mechanical and optical polishing, grinding, cutting and dicing allowing them to extend the range of geometries that are possible.

Source information

Contact:
Dolomite Contact: Dr Gillian Davis, Commercial Director
Tel: +44 1763 242491
e-mail: sales@dolomite-microfluidics.com

Media Contact: Richard Blackburn, Energi Technical Limited
Tel: +44 1603 278228
e-mail: richard@energi-tech.co.uk

Source title

Dolomite Microfluidics

Source Url

http://www.dolomite-microfluidics.com

Micropore Technologies

Thu, 06 Sep 2007 11:37:52 +0100

Ticker Id

Web url

http://www.microporetech.com/

Contact Email

r.g.holdich@micropore.co.uk

Short description

Street address

PO Box 306, Madison

Zip or postal code

07940

Telephone

(973) 822-3877

Fax

(973) 822-3876

Foundation date

Ceo, president

Tom Lewis

Number of employees

Long description

Micropore Technologies, LLC, is based in Madison, NJ and is the sister company of Micropore Technologies, Ltd. (UK), which was established in 2003. These organizations are commercializing products and technology based on novel emulsification processes using their patented metallic membranes. The discoveries for these technologies originated in the department of chemical engineering at Loughborough University (UK). The intellectual property (IP) resides in Micropore Technologies, Ltd., with the University holding an equity position in the company.

The principal inventor, Richard Holdich, is a Professor of Chemical Engineering at Loughborough University. He has published many papers in the field, and is author of a book on Particle Technology (1). His research on surface filter membranes led to the inventions of the emulsification processes capable of forming liquid or solid particles with the average size controlled over a narrow range. Particle diameters can be controlled from as low as 10 microns to 600 microns.

Micropore Technologies has now demonstrated at the pilot scale a proprietary process to disperse water-based ingredients as stable spherical particles in fatty substances, e.g., water in chocolate. Additionally, development work is underway with major industrial companies to form polymeric and other types of particles as suspensions in water, which are subsequently dried to yield mono-disperse solid spheres. One example is the use of these solid particles as chromatography beads. Products based on the technology are under development in the US and Europe, although the range of applications still needs to be more fully explored.

The following is a partial listing of applications for the technology:

* Encapsulation of aqueous particles as an emulsion in fatty compounds that can be used for
* Low fat confections
* Delivery of nutraceuticals
* Specialized creams
* Formation of mono-disperse chromatography resins.
* Multi-component particle formation for controlled release of drugs, with the active pharmaceutical
* ingredient encapsulated in a ‘release’ phase, and the coated drug is dispersed in a fluid medium. Encapsulation and isolation of mammalian cells in defined sized droplets.

Additional Commentaries and remarks

Patents

Ingeniatrics S.L.

Benj — Mon, 06 Aug 2007 14:44:14 +0100

Ticker Id

Web url

http://www.ingeniatrics.com/

Contact Email

info@ingeniatrics.com

Short description

Street address

Avd. Américo Vespucio 5-4, 1a p., mod. 12

Zip or postal code

Telephone

+34 954 081 214

Fax

Foundation date

Ceo, president

Ph.D Alfonso Gañan Calvo

Number of employees

Long description

Our technology is based on a proprietary microfluidic platform called Flow Focusing. Flow Focusing Technology is based on a combination of specific geometry and hydrodynamic forces, making it a very versatile microfluidic system. The phenomenon is characterised by the presence of a steady micro-jet which is “sucked” through a small orifice, and breaks up into well defined droplets within the micro and nanometric range. Solidification of these particles gives rise to capsules with infinite applications. Nowadays, our engineers and scientists have developed and optimized the technology, achieving particles smaller than 1 microns without using external excitation. Flow Focusing is patented internationally, with coverage in the USA, Europe and Asia.

Additional Commentaries and remarks

Patents

Fluigent

Benj — Mon, 23 Jul 2007 17:31:48 +0100

Ticker Id

Web url

http://www.fluigent.com/

Contact Email

Short description

Street address

4 Avenue de l'Observatoire

Zip or postal code

75006

Telephone

0033 (0)1 53 73 15 51

Fax

0033 (0)1 53 73 15 52

Foundation date

Ceo, president

Number of employees

Long description

Our current products include the MFCS series of microfluidic flow control systems, based on the proprietary FASTAB™ technology. Fundamental studies in micro or nano hydrodynamics, nanoliter dispensing, fast mixing, bioassays, hybridization arrays, lab-on-chip electrophoresis, micro-TAS, perfusion and accurate control of cells environment, flow cytometry, combinatorial chemistry, diagnosis, are a few examples of applications in which MFCS can make your life much easier, and open unbounded routes to your imagination.

Fluigent will also introduce soon on the market innovative matrices for capillary electrophoretic detection of unknown mutations. Based on the proprietary EMMA™ technology, validated at Curie Institute's hospital for the detection of mutations. These matrices are compatible with most existing capillary DNA sequencers, and allow unprecedented sensitivity, throughput and cost effectiveness.

Fluigent, a spinoff of Curie Institute and CNRS, owns or licences a portfolio of issued or pending patents belonging to 7 families, and covering its core technologies in flow control, microfluidic devices, polymers, colloids and analytical methods. Our customers include academic and industrial research laboratories in physics, chemistry, biology, and clinical diagnostic centers. The company's products are sold directly from our Paris headquarters, and will be soon available through distributors worldwide. We also propose OEM products and customized development of building blocks or complete solutions based on our proprietary technologies, for the pharmaceutical and diagnosis industry.

Additional Commentaries and remarks

Patents

CMC Microsystems

Benj — Fri, 06 Jul 2007 11:57:12 +0100

Ticker Id

Web url

http://www.cmc.ca/

Contact Email

Short description

Street address

210A Carruthers Hall, Queen's University

Zip or postal code

K7L 3N6

Telephone

613.530.4666

Fax

613.548.8104

Foundation date

Ceo, president

Number of employees

Long description

Researchers depend on CMC’s services to design, manufacture and test microsystems concepts for future applications in many industrial sectors. CMC offers products and services that include microelectronics, micromechanics (usually implemented in the form of microelectromechanical systems or MEMS), microfluidics, photonics/optoelectronics and embedded software.

Additional Commentaries and remarks

Patents

Phoenix S&T, Inc.

Benj — Mon, 02 Jul 2007 15:23:30 +0100

Ticker Id

Web url

http://www.phoenix-st.com/

Contact Email

Short description

Street address

107 Chesapeake Blvd. Suite 107

Zip or postal code

21921

Telephone

(410)996-9735

Fax

(410)996-9736

Foundation date

Ceo, president

Number of employees

Long description

Phoenix S&T's mission is to work closely with our customers to develop new applications. Even though the chips are targeted for protein applications, virtually any sample now analyzed by mass spectrometry can benefit from the superior performance of nanospray. We encourage all our potential users to contact us with ideas on how our devices may help you solve your problems in proteomics and other areas of applications.

Mission Statement

Phoenix S&T Inc. supplies 3-D microfluidic devices based on microinjection molding of plastics to provide highly flexible designs for a seamless integration into the customer's existing instruments and high-throughput robotics. These devices are groundbreaking in concept, have state-of-the-art performance and are easy to use and affordable. We are dedicated to helping our customers unleash the power of mass spectrometry analyses by working with them to provide the breakthrough technology needed to do their jobs faster, better and cheaper..

Additional Commentaries and remarks

Patents

IQ Micro Inc.

Benj — Tue, 22 May 2007 11:54:19 +0100

Ticker Id

Web url

http://www.iq-micro.com/

Contact Email

info@iq-micro.com

Short description

Street address

500 Australian Avenue S., Suite 700

Zip or postal code

33401

Telephone

561-514-0118

Fax

561-514-0195

Foundation date

Ceo, president

Number of employees

Long description

This pump can be integrated in large numbers on a single chip. It contains no moving parts and is built using materials 100 to 10,000 times smaller than a human cell.

These microactuators are capable of being mass-produced and will enable drastic reductions in the sizing of an expansive range of medical and industrial equipment.

We believe our competitive advantage lies in the ability of our solution to pump liquids using only a few volts of AC power delivered via electrodes inside the pump.
All components of the company's technology are patent protected in the U.S. and nine other countries.

Additional Commentaries and remarks

Patents

RainDance Technologies, Inc. ( RDT )

Benj — Wed, 25 Apr 2007 15:37:52 +0100

Ticker Id

Web url

http://www.raindancetechnologies.com/

Contact Email

rdtinfo@raindancetechnologies.com

Short description

Street address

530 Whitfield Street

Zip or postal code

06437

Telephone

Toll Free Phone: 866.896.3128, Phone: 203.458.2947

Fax

203.458.2514

Foundation date

Ceo, president

Number of employees

Long description

The PLS™ is an integrated fluid handling system that provides precise manipulation of minute amounts of fluids for a variety of industrial and research applications:

* Life Sciences Research
* Enzymes / Microorganisms for Industrial Biofuels
* Cancer Diagnosis / Detection for Residual Disease

Founded in 2004 by scientists from Harvard University in Boston, the Medical Research Centre in Cambridge, and the ESPCI in Paris, RainDance Technologies designed the Personal Laboratory System to be the chemical equivalent of a personal computer. The key to this innovation is the first combination of microdroplets and microfluidic systems to create digital packets of chemical information called NanoReactors™. Like a computer manipulates bits of information, the PLS enables the programmable handling of cells and fluid samples for innovative assay and screening applications. The promise of this technology has allowed RainDance to attract an outstanding Scientific Advisory Board including three Nobel Prize winners: Jean-Marie Lehn, Sir Aaron Klug, and Dr. Richard Roberts, as well as Sir Gregory Winter.

Additional Commentaries and remarks

Patents

Dolomite

Benj — Thu, 29 Mar 2007 17:29:33 +0100

Ticker Id

Web url

http://www.dolomite-centre.com/

Contact Email

Short description

Street address

Syrris Ltd. 27 Jarman Way, Royston Herts

Zip or postal code

SG8 5HW

Telephone

+44 (0)1763 242 555

Fax

+44 (0)1763 242 992

Foundation date

Ceo, president

Number of employees

Long description

In-house glass microfabrication facilities allow rapid prototyping of glass chips along with ability to ramp up to high volume manufacture. Flexible processing gives a choice of glass types and thicknesses along with processing in quartz and ceramics.

Dolomite offers a unique combination of services from device fabrication and design through to instrument and technology development.

Dolomite is a one-stop shop for glass microfluidics. We work closely with customers to develop devices, systems or processes. The benefits of working with Dolomite include:

* Chip designs can be prototyped and tested rapidly
* A wide range of device geometries are possible with our flexible fabrication processes
* Access to a team with extensive experience developing microfluidic devices and systems
* We will provide solutions that are innovative, robust and complete

Additional Commentaries and remarks

Patents

Advanced Liquid Logic, Inc.

Benj — Thu, 01 Mar 2007 12:08:50 +0000

Ticker Id

Web url

http://www.liquid-logic.com/

Contact Email

info@liquid-logic.com

Short description

Street address

615 Davis Dr, Suite 800

Zip or postal code

27560

Telephone

919-287-9010

Fax

919-287-9011

Foundation date

Ceo, president

Number of employees

Long description

Digital microfluidics is a lab-on-a-chip approach based on direct, programmable micromanipulation of small volume droplets using electrical fields. Digital microfluidics enables complex, multi-step liquid handling protocols to be flexibly, scalably, and cost effectively implemented.

Why is digital microfluidics a fundamentally better approach?

* Programmable, software-driven, discrete electronic control of each droplet provides amazing flexibility
* The channel-less architecture is easily reconfigurable with only software changes
* Very accurate and repeatable droplet volumes lead to high quality test results
* The control equipment is small and inexpensive and extremely energy efficient
* Discrete droplet control and no channels to prime translates to efficient use of samples and reagents
* Development cycles are short using industry-standard, low cost, production-ready printed circuit board fabrication technology
* There are no pumps or valves - no moving parts at all!

Additional Commentaries and remarks

Patents

Micronit Microfluidics

micronit — Wed, 28 Feb 2007 12:09:43 +0000

Ticker Id

Web url

http://www.micronit.com/

Contact Email

info@micronit.com

Short description

Street address

Colosseum 15

Zip or postal code

7521 PV

Telephone

+31 53 850 6 850

Fax

+31 53 850 6 851

Foundation date

Ceo, president

Ir. Micha Mulder

Number of employees

Long description

Micronit is a world leader in developing, prototyping, and manufacturing of lab-on-a-chip products. Micronit has extensive experience supplying microfluidic solutions to the life sciences and chemistry industry.

Experience & Know-How
A unique combination of expertise in microfluidic engineering and experience in glass micromachining allows Micronit to create customized microfluidic devices for various applications. Micronit engineers have more than 80 years of experience designing and manufacturing microfluidic devices.

Quality, Innovation & Volume
In close cooperation with customers, Micronit designs and develops prototypes of lab-on-a-chip devices. Once a functional prototype is thoroughly developed and tested, Micronit can manufacture it in high volume. Micronit is a flexible partner who understands the needs of customers and the critical challenges facing microfluidic technology.

Key characteristics of Micronit products and services are their high quality and accuracy. During design for manufacturing, special care is given to the reproducibility of products. Every product that Micronit supplies is fully traceable.

Inside Life Sciences
More and more developments in life sciences are based on microfluidics. Modern day analytical instruments used in blood analysis, air control and DNA sequencing have lab-on-a-chip devices inside, enabling fast and efficient analysis.

Micronit finds itself in the middle of life sciences. Micronit products are developed for analytical instruments used in pharmacy, biotechnology, medicine and ecology. The application of lab-on-a-chip technology results in faster analysis, decreased reagent consumption, and decreased cost per analysis.

Microfluidic applications
The Micronit R&D department looks forward to developing a lab-on-a-chip device for your application. Previous collaborative projects resulted in:

Chips for Capillary Electrophoresis
Microreactors
Micromixers
Flow Splitter Chips
Chips with Electrodes
Flow Restrictors
Microcoolers
Microneedles
Microtiter Plates
Microarrays
Chips with Particle Traps

Additional Commentaries and remarks

Patents

Memsstar technology

Benj — Wed, 21 Feb 2007 13:55:27 +0000

Ticker Id

Web url

http://www.memsstar.com/

Contact Email

Short description

Street address

Starlaw Park, Starlaw Road

Zip or postal code

EH 54 8SF

Telephone

+44 (0)1506 414582

Fax

+44 (0)1506 464300

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Ceo, president

Number of employees

Long description

APPLICATIONS
Process Steps;
Coatings, Surface Activation, Silicon Etch and Release, Oxide Etch and Release, Polymer Removal

Micro Systems;
Sensors, RF MEMS, Microdisplays, Microfluidics, Acoustics, ....

Structures;
Membranes, Cantilevers, Microfluidics, Microbridges.

USA office:
memsstar technology
2009 RR 620 North
Suite 310
Austin, TX 78734
Phone 512-266-0196
Toll Free 866-291-0196

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Patents

Cellix Ltd

Benj — Fri, 16 Feb 2007 15:25:50 +0000

Ticker Id

Web url

http://www.cellixltd.com/

Contact Email

info@cellixltd.com

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Street address

Unit 3.81, Institute of Molecular Medicine, Trinty Centre for Health Sciences, James's Street

Zip or postal code

Telephone

+353-1-8963182

Fax

+353-1-8962771

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Ceo, president

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These biochips allow detailed dissection of disease processes at the cellular level where shear stress or continuous flow parameters are known to affect physiologic events. This innovation embodies the vista of microfluidics and nanotechnology furnishing the benefits of reduced sample and reagent volume (microlitre range), speedy assay time combined with the potential for automation and parallel processing.

Cellix gratefully acknowledge the support of Enterprise Ireland and their Commercialisation Funding Programme.

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BIOIDENT Technologies, Inc.

Benj — Thu, 07 Dec 2006 10:43:04 +0000

Ticker Id

Web url

http://www.bioident.com/

Contact Email

info@bioident.com

Short description

Street address

3000 Sand Hill Road Building 1, Suite 170

Zip or postal code

94025

Telephone

+1 650 391 4247, 48

Fax

+1 650 561 9303

Foundation date

Ceo, president

Number of employees

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BIOIDENT is the first and only company to combine printed optoelectronics with microfluidics to create a new class of photonic lab-on-a-chip systems, which enable real-time, multi-parameter detection and analysis capabilities. BIOIDENT allows for the first time to integrate full optical readout systems directly onto microfluidic devices. BIOIDENT´s lab-on-chip systems will be used for mobile water and food analysis, chemical and biological agent detection and In-vitro diagnostics. BIOIDENT is a wholly owned subsidiary of NANOIDENT Technologies AG, the technology leader in the development and manufacture of printed organic semiconductor-based photonic solutions.

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LabSmith

Benj — Thu, 26 Oct 2006 15:33:53 +0100

Ticker Id

Web url

http://www.labsmith.com/

Contact Email

info@labsmith.com

Short description

Street address

7665 Hawthorne Ave

Zip or postal code

94550

Telephone

(925) 292-5161

Fax

(925) 454-9487

Foundation date

Ceo, president

Number of employees

Long description

Our equipment is designed by seasoned researchers — we know that every hour of actual data-gathering represents one hundred late-night hours with loose wires, noisy signals, failed runs and aggravation. But we also believe it doesn't have to be this way, not even for the most cutting edge research.

The company was founded in 1995 by Dr. Eric Cummings, an active researcher in microfluidics, gas dynamics, and laser diagnostics. Dr. Cummings' work at Caltech and other institutions pointed out the need for a new approach to research design. By developing reliable "building blocks" for high-speed timing and coordination, LabSmith provided an alternative to the home-made control systems that plague so many labs. Word spread about the reliability and ease of use of these products, and researchers in fields from automotives to gas dynamics began improving their lab efficiency with our systems.

Since then, LabSmith has increased its product offering to address other exasperating aspects of research. These products have defined "innovation," introducing entirely new methods such as high voltage sequencing, and real-time monitoring and recording of microfluidic systems.

In laboratories around the world, LabSmith products have become trusted, indispensable equipment. From snap-together microfluidics to affordable, feature-laden microscopes, look to LabSmith for innovative solutions to your research problems.

Nanotechnology : Microfluidics

New Platform for Microfluidics Research

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Clearing the US and EU Regulatory Path to Product Approval – “What Similarities and Differences Exist and How Can Companies Mana

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Sigma-Aldrich Corporation

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Dolomite's Microfluidic Reactor Chip Enables Powerful Flow Chemistry Technology

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Dutch Wafers to Study Early Universe

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Micropore Technologies

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Ingeniatrics S.L.

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