Advanced Gene Mapping Course
The Rockefeller University, New York
Monday through Friday, December 13-17, 2010
Emphasis of this course is on the analysis of complex human disease traits; concentrating on methods to map both common variants through genome wide association studies (GWAS) as well as detecting associations with rare variants using next generation sequence data. The course will include theory as well as practical exercises. The exercises will be carried out using a variety of computer programs. TOPICS include: Analysis of whole genome association studies; analysis of rare variants; qualitative and quantitative traits; population and family based; controlling for population substructure (principal components analysis); data quality control; imputation of genotype data; meta analysis; gene x gene interaction; sample size estimation; evaluating power and significance levels for genetic studies; permutation; False discovery rate and controlling for multiple testing. The instructors for the course are: Goncalo Abecasis (University of Michigan), Heather Cordell (University of Newcastle), Christoph Lange (Harvard University), Suzanne Leal (Baylor College of Medicine & The Rockefeller University) and Shaun Purcell (Harvard University). This course is supported by a grant from the National Institute of Health – National Human Genome Research Institute and the National Institute of Mental Health
The cost of the 5-day course is $100. This fee covers tuition and course related expenses (handouts, etc.) but not room and board. Seven travel stipends of up to $1,300 each are available to eligible participants from U.S. institutions. Eligibility requirements are: (1) sufficient background and practical experience in statistical analysis of genetic data, and (2) demonstrated financial need. Preference for stipends will be given to pre-doctoral students and postdoctoral researchers.The maximum number of participants is 20.
For additional course information and course application please visit the course website: