Sealed fluid cell with flow-through possibility and temperature control starting with -30 up to +170 оC range (and -10 +120 оC in liquid).The cell has high 0.005 оC thermal stability and perfect range of sample positioning 1x1 mm (limited by membrane) with positioning accuracy up to 5 um. As compared to the already existing cells for operation in liquid the new one offers broader temperature range. For SPM operation in air environment with cooling (down to -30C) special traps have been integrated to prevent the sample from water vapor condensation. New options have been designed for obtaining the most reliable measurements in controlled environment for experiments led in the fields of biology and chemistry and for new materials developing and testing.